Prevalence of Frailty in Heart Failure Patients in 1.1 million sized adult population of Mid & South Essex. Findings support recommending a “Frailty First” approach to managing Heart failure
Prevalence of Frailty in Heart Failure Patients in 1.1 million sized adult population of Mid & South Essex. Findings support recommending a “Frailty First” approach to managing Heart failure S Zaidi; R Thakkar Background: Heart failure (HF) and frailty have a bidirectional relationship. Although people with HF experience high rates of unplanned hospitalisation, most admissions in those with co-existing frailty are due to non-cardiac causes, including falls, acute kidney injury/electrolyte disturbance and bleeding events, rather than HF itself. These events are frequently related to adverse
Heart Failure and Annual Influenza Vaccination Across the Watling Street Primary Care Network: a clinical audit
Frailty Deterioration in Medical Inpatients: Association with Length of Stay and Therapy Input
Who receives a diagnosis of orthostatic hypotension and is it underdiagnosed in patients with frailty?
Orthostatic Hypotension (OH), defined as a systolic blood pressure (SBP) drop >=20mmHg or diastolic blood pressure (DBP) drop >=10mmHg within three minutes of standing, is associated with falls, cardiovascular risk and cognitive impairment. NICE recommend performing lying and standing blood pressure measurements during falls assessments NG249, 2025. Despite this, OH may being underdiagnosed, a primary care survey showed a symptom driven approach to OH diagnosis that may exclude those with advanced frailty and cognitive impairment McDonagh, 2025. Method Our cohort was 9,052,916 patients aged 60
Evaluating the QUAD Score in Patients Aged ≥80 Years with Heart Failure with Reduced Ejection Fraction
Are NICE recommendations for cardiovascular and diabetes prevention appropriate in moderate-to-severe frailty?
Background: UK guidance increasingly promotes disease-focused prevention strategies. The 2026 National Institute for Health and Care Excellence (NICE) guideline for type 2 diabetes mellitus (T2DM) advocates early initiation of metformin and sodium–glucose cotransporter-2 (SGLT2) inhibitors, while recent NICE cardiovascular prevention guidance supports intensive blood pressure and lipid lowering. In contrast, British Geriatrics Society (BGS) pragmatic prescribing guidance recommends individualised targets and treatment deintensification in people living with moderate-to-severe frailty. Whether
Optimising Blood Pressure Management in Older People Living with Frailty
Appropriateness of Ongoing Valve Clinic Surveillance According to Frailty Status
Improving Heart Failure Management in Older People
Towards a novel multidimensional nursing intervention addressing frailty in people with heart failure: a modified Delphi study
Cardiometabolic disease trajectories and falls risk in older adults: a cohort study using electronic health records
Introduction Cardiometabolic diseases accumulate with age. Falls are a leading cause of injury, hospitalisation and loss of independence in older adults, and individual cardiometabolic conditions are known to increase falls risk. However, it is unclear how the sequence in which cardiometabolic conditions develop influences subsequent falls risk. We aimed to identify common cardiometabolic disease trajectories and estimate their association with incident falls. Method We used UK primary care data (Clinical Practice Research Datalink), linked to hospital admissions data (HES) in a cohort study
Optimising Cardiovascular Care in Ageing Populations: Integrating Geriatric Principles into Contemporary Cardiology
Temporal trends and demographic patterns in hypertension-related mortality with intracerebral hemorrhage in the United States
The implementation of a Cardiogeriatrics Liaison Service at a District General Hospital: a Quality Improvement Project
Introduction The involvement of geriatricians in the care of frail, older patients under other specialities, particularly within perioperative settings, has shown to improve outcomes (1). There is growing support for using Comprehensive Geriatric Assessments (CGAs) within Cardiology, due to the prevalence of cardiovascular disease within this cohort and the challenges frailty presents to clinical decision-making (2,3). Methods Our aim was to increase the percentage of CGAs carried out for patients admitted under Cardiology aged ≥65 with a Clinical Frailty Score (CFS) of ≥5 by 50%, between
Immune checkpoint inhibitor-induced myocarditis in older adults: a systematic review of associated factors
Frailty, Anticoagulation Use and Clinical Outcomes in Older Adults With Atrial Fibrillation: A Prospective Observational Study
To What Extent Has Frailty Been Incorporated Into Heart Failure Interventional Trials? A Scoping Review
Introduction: Chronic heart failure (HF) is highly prevalent in older adults, in whom frailty is common and associated with poorer outcomes. Despite advances in guideline-directed medical therapy, concerns regarding tolerability and polypharmacy contribute to under-utilisation in frail patients. This study aimed to map existing evidence on how frailty is incorporated into HF interventional trials. Method: A scoping review was conducted of Medline, Ovid Embase, Cochrane CENTRAL, and ClinicalTrials.gov for HF interventional studies published up to August 2025 where frailty was assessed using a
Invasive versus conservative medical management in NSTEMI patients aged ≥75 years: A retrospective cohort study
Introduction Invasive and conservative medical management strategies are widely used in the treatment of Non-ST-segment Elevation Myocardial Infarction (NSTEMI). Multiple studies have demonstrated no significant long term survival benefit of invasive management in patients aged ≥75 years old presenting with NSTEMI compared to conservative management. Therefore, the optimal management strategy in this age group remains uncertain. Purpose To investigate the 2-year major adverse cardiovascular events (MACE) as the primary outcome in patients aged ≥75 years old presenting with NSTEMI and managed
Door-to-needle performance and areas for improvement of reperfusion therapy in acute ischaemic stroke
Introduction Door-to-needle (DTN) time and timely transfer for mechanical thrombectomy (MT) are key modifiable determinants of outcome in acute ischaemic stroke. We assessed reperfusion pathway performance and variables affecting DTN and door-to-departure (DTD) times in MT patients to identify areas for improvement. Method We retrospectively reviewed 239 consecutive patients directly admitted to Northampton General Hospital, University Hospitals of Northamptonshire NHS Trust, who underwent reperfusion therapy (rtPA, referred for MT, or both) between January 2025 and May 2026. Time intervals
Prehospital Video Triage for stroke: evaluation of the PVT service
Introduction: Prehospital vide triage offers the potential to improve prehospital decision-making before hospital arrival. This study aimed to evaluate the newly introduced Prehospital Video Triage (PVT) service for suspected stroke patients at Northampton General Hospital, University Hospitals of Northamptonshire NHS Trust. Method: A retrospective comparative analysis was conducted of two cohorts: patients triaged via the standard non-PVT pathway (n = 229) and patients assessed via the PVT service (n = 308), covering the period January to May 2026. Both groups included only calls originating