Establishing a Foslevodopa–Foscarbidopa Service within a geriatric medicine Parkinson’s service
Introduction Our movement disorder service provides care for people living with Parkinson’s across 4 boroughs and 2 acute hospitals. There are predicted to be 1,671 people living with Parkinson’s in our area1. Foslevodopa-foscarbidopa is indicated for the treatment of advanced levodopa-responsive Parkinson’s with severe motor fluctuations when available combinations of medications have not given satisfactory results and apomorphine or deep brain stimulation (DBS) are no longer effective or not appropriate2. Method Our service aims to proactively identify patients who are living with advance
Optimising fall risk classification models in Parkinson’s disease utilising clinical and mobility outcomes
Background: Falls are a serious concern for people with Parkinson’s disease (PD), often leading to hospitalisation, dependence and reduced quality of life. Effective fall management requires identification of those at risk. Although many clinical and mobility-related outcomes have been linked with falls, it remains unclear which selection of outcomes best discriminate fallers from non-fallers. Methods: Participants with PD were recruited as part of the ICICLE-GAIT study. Data presented are from the 54-month and 72-month follow-up. Participants were stratified into fallers and non-fallers based
Interventions and outcomes with a Parkinson’s Disease Fellow Home Visit Service
What Non-Genetic Parkinson’s Disease Risk Factors are Africans Exposed To? A Scoping Review
Improving Bone‑Health Assessment in Parkinson’s Disease: A Completed Audit Cycle and Quality‑Improvement Project
Evaluate doctors' knowledge and practice in managing Parkinson's disease during acute admissions.
Introduction Patients with Parkinson’s Disease (PD) frequently experience delays or missed doses of time-critical medications, leading to worsened symptoms and prolonged stays. This issue is thought to be partly due to gaps in doctors’ knowledge and prescribing practices. Therefore, this project uses a survey to assess staff knowledge and practices and identify gaps in managing Parkinson’s medications in acute and complex clinical scenarios. Methods: A questionnaire was distributed to 26 doctors across adult medical wards and the Emergency Department, including consultants and trainees. The
A Cerner-based Electronic Prescribing and Medicines Administration (EPMA) Parkinson’s Medicines Care Plan Reduces Time-Critical Medication (TCM) Errors
DAT Imaging as a Clinical Decision Tool in Parkinsonism: A Two-Year Audit from a North Welsh UK Movement Disorder Service
Background: Diagnosing Parkinsonism remains a common and clinically significant challenge within movement disorder services, particularly in early disease and in atypical or non-motor–predominant presentations. Dopamine transporter (DAT) imaging is recommended by NICE where diagnostic uncertainty persists; however, real-world evidence demonstrating its impact on clinical decision-making beyond diagnostic confirmation remains limited. Methods: We conducted a retrospective audit of all DAT scans requested within a UK specialist movement disorder service between January 2023 and December 2024
Transforming Parkinson's Disease Care Through Digital Wearables: A Patient-Centred Approach
Improving Quality of Movement Disorder Care for Nursing Home Residents
Introduction Within the Older Person’s Medicine Movement Disorder service at Newcastle upon Tyne Hospitals, we were aware people with Parkinson's (PWP) living in nursing care were not necessarily receiving the same quality of care as other PWP. We have developed a nursing home movement disorder clinic to address this. Methods Practically, approximately 15% of PWP were identified as living in nursing care. After review of the geography and numbers, one consultant and specialist nurse clinic were allocated a month to facilitate care home visits to all PWP within 6 months. After identifying PWP
A service evaluation of the methods and efficacy of the South Manchester Parkinson’s service in diagnosing and managing Parkinson's Disease Dementia
Introduction Parkinson’s disease dementia (PDD) is characterised by years of motor symptoms preceding cognitive decline, particularly presenting with declining executive function, attention, visuospatial abilities, and psychiatric symptoms. The motor symptoms of Parkinson’s disease are managed under a Parkinson’s and movement disorder service led by geriatricians or neurologists and should involve a multidisciplinary team. When dementia symptoms develop, patients are generally referred to a memory service led by old age psychiatrists with dementia support advisors and admiral nurses available
A Service Evaluation of the Barriers and Facilitators to rehabilitation faced by Hospitalised Older Parkinson’s Patients at Great Western Hospital (GWH); as viewed by clinicians
Aims/Purpose: To assess the barriers and facilitators for rehabilitation in the older Parkinson’s Disease (PD) patient population that have been admitted to Great Western Hospital (GWH); as viewed by clinicians who work within the acute inpatient setting. This was accomplished through an internal service evaluation project designed to create a GWH-specific action plan, which may also have broader applicability. Methods: A review of the related literature informed the development of interview questions, which guided 20 semi-structured interviews with clinicians conducted in collaboration with
Real-world effects of foslevodopa/foscarbidopa on gait and balance in people with Parkinson's
Introduction: Foslevodopa-foscarbidopa (Produodopa) is a new subcutaneous infusion run continuously over 24 hours for people with Parkinson’s (PwP). Foslevodopa is a prodrug for levodopa, the most effective treatment for Parkinson’s symptoms. Studies demonstrate that Produodopa improves symptom fluctuations (i.e. less OFF time & less troublesome dyskinesia) compared to oral medications. Gait and balance impairment are key risk factors for falls in advanced Parkinson’s and are less levodopa responsive. However, the impact of Produodopa on gait and balance has not yet been described. Methods
Analysing Motion Capture Kinematics to aid Clinical Assessment and Physiotherapy Strategies in Progressive Supranuclear Palsy
Motor profile and measures of physical function in people with Parkinson's disease in northern Tanzania
Quality Improvement Project on Fragility Fracture Risk Assessment using FRAX score in Older Adults in Inpatient Psychiatry Unit
Cognitive function in people with Parkinson’s disease in northern Tanzania.
Known, and unknown, hypertension in the Transforming Parkinsons care in Africa ( TraPCAf) cohort: pilot data
Mortality and Institutionalisation Following de Novo Use of Rotigotine Patches in Hospitalised Patients with Parkinson’s Disease
Music: Reclaiming the Sense of Self in People Living with Alzheimer's Disease
Introduction: Alzheimer’s disease (AD) is a progressive neurodegenerative disease, characterised by memory and cognitive impairment. Autobiographical memory, or the memory of oneself, consists of episodic, self-defining and semantic components. AD profoundly disrupts autobiographical memory, causing individuals to lose their self-identity. Although previous research has shown that music can facilitate the recall of autobiographical memories, the extent and nature of this effect in AD is unclear. Specifically, it is debated whether music preserves neural networks involved in autobiographical