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How does a diagnosis of Dementia with Parkinson's influence care setting in the future?

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Aju Rafeeq MBBS 1; Chris Thomas FRCP MBBS 2; Jyothi Adenwalla MBBS, MS 2; Sarah Page, MRCP MBBS 2; Biju Mohamed FRCP, MBBS 2.
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INTRODUCTION Dementia in Parkinsons is common and under-recognised with a significant impact on person and their carer. Contrary to other services, Cardiff and Vale Parkinson's services run an integrated Parkinson's clinic where People with Parkinsons (PwP) developing dementia continue to be managed by the same clinical team. METHODOLOGY An review of 425 patients diagnosed with dementia with a background of Parkinson's over last 10 years was undertaken. A random sample of 50 patients assessed for demographics, duration of Parkinson's, presentation of dementia and outcomes including place of

Adding value to the clinically optimised patient experience through a clinically optimised pathway

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Madiwilage M U Gunarathna¹, Shreya Podder¹, Bethan Bowen¹, Zoe Griffiths¹, Angela Puffett,¹ Tessa Phillips² and Laura Rogers²
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Introduction High number of clinically optimised patients in a DGH were having daily clinical input. RAAC clinical incident resulted in movement of clinically optimised patients from the district general hospital to a community hospital increasing the community bed base from 32 to 72. This gave the opportunity to review how these patients were managed. Method It was recognised that a daily medical ward round for clinically optimised patients was neither necessary or optimal and potentially perpetuated the impression that patients required in hospital care. National guidance supports delegation

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Early Supported Discharge for Fragility Fractures -Collaborative Working to Deliver Responsive High Quality Patient-Centred Care

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E.K.Davies 1; C.J.Beynon-Howells 2; A.J.Burgess2; A.Mehta1; K.Ng3; E.A. Davies1,2.
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Introduction During 2022, non-femoral fractures that didn’t require operative management had 30 days median inpatient length of stay (LOS) at SBUHB. Femoral fracture patients >65 years had LOS 36 days (GIRFT average 19 days), with 720 admissions. High local incidence is believed to be contributed by historical failures to identify and treat non-femoral fragility fractures. A new service was created from a collective effort to do better for our patients and prevent avoidable harm by breaking down barriers between services and promoting effective collaborative working. Methods A collaboration

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A Novel Frailty Specific Same Day Emergency Care (SDEC) Score – An Initial Retrospective Validation Cohort.

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A.J. Burgess; K.H. James; T.B. Maddock; D.J. Burberry; E.A. Davies.
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Aim: Several scores have been developed to identify SDEC patients from Emergency Department (ED) triage and acute medical intakes. Scores are designed to improve system efficiency, overcrowding and patient experience but none have been developed for older adults. Previous work has shown that existing scores e.g. Glasgow Admission Prediction Score, Sydney Triage to Admission Risk Tool and the Ambulatory Score were not able to predict admission in our population(1). We have developed a novel, frailty-focused score. Methods: The Older Person’s Assessment service (OPAS) is ED based, accepting

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Patient Experience and Outcome Measures in Virtual Wards at Swansea Bay University Health Board.

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A.J.Burgess1; A.Mehta2; E.K.Davies2; N.Hapgood2; E.A. Davies1,2.
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Introduction Swansea Bay Health Board is covered by eight community clusters (240 virtual beds), each with their own Virtual Ward (VW) MDT which provides community based Comprehensive Geriatric Assessment and reablement. The VW governance structure includes the routine collection of person centred metrics. There is no recognised PROM or PREM specifically designed for needs of frail older people and PROMs and PREMs are rarely used to inform quality and continuity in services at transitions of care (e.g. at discharge from hospital) Methods VW data from June 2023 to February 2024 was analysed

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Improving the identification of Frailty in the Emergency Department

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A Cosimetti, Y Zhang, A Montagu
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Introduction – NHS England have included the identification and response to frailty in emergency departments (ED) as an area of clinical priority, producing the CQUIN05. At the Oxford University Hospitals Trust (OUH) we have designed a front door frailty service and are participating in the CQUIN05 scheme. The Clinical Frailty Scale (CFS) score is recorded by nurses in ED. Following the CQUIN05 criteria, patients aged above 65 years old and scoring 6 or above on the CFS (moderately frail) are identified by the front door frailty service and a comprehensive geriatric assessment (CGA) initiated

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Routine delirium assessment for patients with hip fracture - using local data to inform the redesign of a national audit

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C Wood1; I Inayat1; L Green1; J Zhu1; D Agius1; SH Bae1; R Michael1; A Johansen1
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Introduction  The National Hip Fracture Database (NHFD) is the mandatory national clinical audit for patients presenting with hip fracture. Since 2007, the NHFD has made admission cognitive assessment using the Abbreviated Mental Test Score (AMTS) routine for people presenting with this injury. In 2024, the NHFD plans to replace the AMTS with the 4A test (4AT), so all patients are additionally assessed for delirium on presentation. This study aims to compare the AMTS and 4AT for this patient group, so the NHFD and our local team can anticipate the consequences of this change in patient

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Change in Frailty Status in the 12 Months Following Solid Organ Transplantation A Systematic Review and Meta-analysis

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A Bevan1; J Avery1; HL Cheah1; B Carter2; J Hewitt3
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Introduction With recent advances in surgical techniques and immunosuppressive therapy, solid organ transplantation (SOT) is increasingly accessible to older and more complex patients. Multiple previous studies have shown quality of life improvements in SOT patients post-transplant across age group and despite significant pre-transplant frailty. As such, we are investigating if SOT is associated with a reduction in frailty status post-tranplant. Methods Studies across five databases between 2000 and 2023 were included if an objective frailty status measurement was used, SOT was performed

Observation Cohort Study of Clinical Frailty Status and Fragility Fractures in a Rural Welsh Hospital

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HL Cheah1; J Hewitt2; S Aithar2; I Singh2
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Introduction Current NICE guideline recommends the use of either the FRAX or Qfracture score to assess the probability of future fragility fractures before measuring a patient’s bone mineral density. However, Qfracture has poor predictive ability in patients above the age of 85. As such, we investigated if the addition of clinical frailty status may enhance Qfracture risk prediction in an older age group. Methods Data were collected from consecutive admissions to an Emergency Frailty Unit (EFU) ofoin Ysbyty Ystrad Fawr Hospital, between 1 April 2015 to 31 March 2017. Demographic information

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Metabolic syndrome and its association with oncogenesis in a follow- up period of a South American geriatric cohort.

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Celis J1; Dulcey L1; Gomez J1; Botello F1; Castillo J1; Theran J2; Jaimes J1; Torres P1;-Ramirez V1; Villamizar E1; Castillo S1; Ciliberti M1; Blanco E1; Gutierrez E1; Ramos G1; Ramos J1; Angulo R1; Acevedo D1; Lizcano A1; Amaya M1; León A2; Estévez M1.
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Introduction: Metabolic syndrome has been associated with an increased risk of cancer. This study evaluated this association in a South American cohort. Methods: Retrospective observational study in 100 patients older than 60 years with metabolic syndrome for more than 10 years from a hospital outpatient center. Anthropometric (waist circumference, body mass index), biochemical (triglycerides, HDL cholesterol, fasting glucose) and clinical (arterial hypertension, type 2 diabetes mellitus) parameters were evaluated. The association between metabolic syndrome, its components and cancer risk was

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Secondary prevention of hip fracture – surveying clinicians' reasons for not using IV Zoledronate in the UK and other countries

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YuenKang Tham; Antony Johansen; Opinder Sahota; Frances Dockery; Alison J. Black; Alasdair M.J. Maclullich; M. Kassim Javaid; Emer Ahern; Celia L. Gregson
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Introduction A quarter of people with hip fractures sustain another fragility fracture within 5 years, but most receive no osteoporosis medication as secondary prevention. To coincide with the publication of ‘A call to action: a five nations consensus on the use of intravenous zoledronate after hip fracture" Age and Ageing, September 2023, we set out to explore clinicians’ reasons for not previously using zoledronate (IV Zol). Methods Prior to first presentation of the ‘Call to Action’ at the Global Fragility Fracture Network (FFN) and British Geriatrics Society conferences in autumn 2023, we

FDG-PET Brain Imaging in Patients Presenting with Cognitive Decline in Cardiff & the Vale

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SY Ow1; C Shute2
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Introduction: Symptom heterogenicity in dementia subtypes can pose diagnostic challenges, leading to potential misdiagnoses and significant implications on patient management. The NICE Guidelines for Dementia 2018 [NG97] recommend FDG-PET where diagnostic uncertainty remains after initial assessment. From 2021, a national and collaborative initiative supported using FDG-PET brain imaging for dementia in Wales to facilitate more accurate and timely diagnoses with higher degrees of confidence. This project aimed to evaluate the temporal aspects and diagnostic accuracy of FDG-PET utilization in

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A retrospective analysis of outcomes in inpatient fallers who sustain a Neck of Femur fracture

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Lee H, Green S, Dickenson C, Russ J, Roberts M, Ng K
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Introduction Inpatient fallers make up the minority of neck of femur fractures (NOF) in Morriston Hospital but it was observed that outcomes were less favourable than those in patients who sustained their fracture outside of hospital. Method Retrospective analysis was conducted of all NOF patients managed in Morriston Hospital whose injury was the result of an inpatient fall between January 2022 and December 2023. Outcomes were compared to those in all other NOF patients including pathological and occult fractures managed in the centre over the same two year period. Anonymised data were

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Improving the communication of a perioperative comprehensive geriatric assessment following admission for emergency surgery

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R Eastwell1, J Kareem2, A Chandler1, S Ham1, N Jardine1, N Humphry1
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Introduction Information-sharing between primary and secondary care is vital for patient safety and reducing duplication. The Electronic Discharge Summary (EDS) enables this but is often incomplete due to time pressures and poor team continuity. Information from the Comprehensive Geriatric Assessment (CGA) by the Perioperative care of Older People undergoing Surgery (POPS) team is often omitted, leading to queries from primary care colleagues and duplication of work on readmission to hospital. Methods Eight core CGA components were determined for inclusion in the EDS. Twenty EDS were reviewed

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Rotigotine Patch Dosing in Parkinson’s Disease: Calculator Discrepancies  

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T Boyle1; C Plowman2; M Rawle3
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Introduction  Converting oral Parksinon’s disease (PD) medications to transdermal Rotigotine is sometimes required when patients have swallowing difficulties. Correct dosing is important to avoid under-treatment and deterioration of PD symptoms. Conversely, excessive dopamine agonist can cause hallucinations and confusion. In the UK, 2 main dose conversion calculators exist: PD Med Calc1 and OPTIMAL2, both utilising different formulae. We compared both to identify any dose discrepancies in their recommendations, and select one for use within revised trust guidelines.  Methods  We conducted a

Towards a Multi-Arm Multi-Stage trial to Accelerate Assessment of Disease Modification in Parkinson’s: The EJS ACT-PD Initiative

Authors' names
Georgia Mills1; Rebecca Chapman2; Sally Collins2; Romy Ellis Doyle1; Cristina Gonzalez-Robles1; Marie-Louise Zeissler2; Thomas Foltynie1; and Camille B Carroll3 on behalf of the EJS ACT PD Consortium.
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Background: Previous clinical trials assessing potential disease-modifying therapies (DMTs) for Parkinson’s disease (PD) have been hugely inefficient in terms of time and resources, resulting in >10 years for a single therapy to complete phase 3 assessment. Additionally, un-representative trial populations limit the generalisability of findings. Increased efficiency of clinical trial conduct has been successfully demonstrated in multi-arm, multi-stage (MAMS) trials, which assess multiple therapies in parallel and identify ineffective therapies at early-stage analyses. New arms can be added

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The impact of a Parkinson’s specialist psychiatrist in the MDT on patient outcomes with Parkinson’s and cognitive impairment

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G Rajesh Nair 1; Dr E Tullo 1, 2; Dr S Henry 2
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INTRODUCTION: Guidance around optimal management of patients with cognitive impairment within a Parkinson’s disease (PD) multidisciplinary team (MDT) is lacking. This project aimed to improve the service pathway by integrating a Parkinson’s disease specialist psychiatrist (PDSP) within the MDT rather than referring patients to a separate mental health service. METHODS: Data including mental health symptoms, time to review, diagnosis, treatment, and follow-up were collected over 12 months from the electronic clinical records of all patients referred to the PDSP with cognitive impairment. This

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The UK Parkinson's Disease Clinical Studies Group

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E Davies; O Bandmann
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The UK Parkinson's Disease Clinical Studies Group The UK has a successful trial scene for Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy neuroprotective studies, but with the growing number of trials, a formal, national structure is required to ensure the successful delivery of the studies. With funding from Cure Parkinson’s, the UK-PD-CSG launched in April-2022. The UK-PD-CSG’s goal is to further develop and support Parkinson’s clinical research across the UK and ensure more people with Parkinson’s (PwP) have the opportunity to participate in clinical trials

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Improving the management of Parkinson's disease at the Surgical departments at Worthing Hospital

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Dr O Shahzad1; Dr P Merrick2; Dr K Patel1; Dr K Lawton2
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1. Introduction Parkinson’s Disease (PD) is a complex neurodegenerative disorder which impacts nearly all aspects of quality of life. Given the known challenges and risks of complications with PD, it is crucial to improve management prior to admission for surgery, in particular accurate medication timing and dose. Therefore a quality improvement project on this subject was initiated. 2. Method A retrospective analysis was conducted of Surgical attendances to Worthing hospital with the aim to identify patients with Parkinson’s disease (PD) admitted under their care. Each patient’s hospital

A Quality Improvement Project into Advance Care Planning Discussions for People with Parkinson’s Disease in York

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Megan Freemantle, Nicholas Latcham
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Parkinson's Disease (PD) is a progressive neurological disorder for which there is currently no cure. Palliative care should be discussed as part of PD management, both to empower patient understanding and expectations of their condition and to avoid unnecessary hospital admissions Results from the 2022 Parkinson’s UK national audit, found that the elderly care PD service in York was underperforming in having advance care planning (ACP) discussions with PD patients. The aim of this quality improvement project is to further review ACP discussions on a larger sample size and improve practice in

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